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New study shows positive correlation between COVID-19 deaths and flu immunization

A new study published by Peer J  last October 1, 2020 shows that there is a positive association between COVID-19 deaths and influenza vaccination rates in people aged 65 years and above. The author said, “the influenza vaccine may increase influenza immunity at the expense of reduced immunity to SARS-CoV-2 by some unknown biological mechanism”. 

The study also showed no correlation between COVID deaths and the degree of lockdowns and mask usage. The author added that ineffective masks could be counterproductive. 

Editor’s Note: In the absence of a COVID-19 vaccine, several countries have taken to providing flu and pneumonia vaccines for its at-risk populations. This new study shows us that this decision may actually be counterproductive, and may in fact cause harm [see Flu shots in South Korea kill 83].

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Positive association between COVID-19 deaths and influenza vaccination rates in elderly people worldwide

Positive association between COVID-19 deaths and influenza vaccination rates in elderly people worldwide

Background The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is an ongoing global health crisis, directly and indirectly impacting all spheres of human life. Some pharmacological measures have been proposed to prevent COVID-19 or reduce its severity, such as vaccinations. Previous reports indicate that influenza vaccination appears to be negatively correlated with COVID-19-associated mortality, perhaps as a result of heterologous immunity or changes in innate immunity. The understanding of such trends in correlations could prevent deaths from COVID-19 in the future. The aim of this study was therefore to analyze the association between COVID-19 related deaths and influenza vaccination rate (IVR) in elderly people worldwide. Methods To determine the association between COVID-19 deaths and influenza vaccination, available data sets from countries with more than 0.5 million inhabitants were analyzed (in total 39 countries). To accurately estimate the influence of IVR on COVID-19 deaths and mitigate effects of confounding variables, a sophisticated ranking of the importance of different variables was performed, including as predictor variables IVR and some potentially important geographical and socioeconomic variables as well as variables related to non-pharmaceutical intervention. The associations were measured by non-parametric Spearman rank correlation coefficients and random forest functions. Results The results showed a positive association between COVID-19 deaths and IVR of people ≥65 years-old. There is a significant increase in COVID-19 deaths from eastern to western regions in the world. Further exploration is needed to explain these findings, and additional work on this line of research may lead to prevention of deaths associated with COVID-19.

https://peerj.com/articles/10112

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